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Stress is a prevalent risk factor for over 75% of both physical and mental health conditions, contributing to elevated morbidity and mortality rates (133)

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However, there are a few notable observations that may have been impacted by the probiotic supplement (visit 3) during antimicrobial treatment compared to placebo that warrant further investigation such as, 1) an increase in the family of Porphyromonadaceae (genus Parabacteroides ) and 2) a relative decrease in the diversity of Enterobacteriaceae from the shotgun sequencing results (Fig