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Comment: Several commenters requested additional stratification factors for public reporting of the measure

Dosing and follow-up times varied

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Similar to the effects of calycosin, silencing of AIM2 also reversed MSU-induced apoptosis in monocytes and macrophages, indicating that calycosin can suppress apoptosis by deactivating the AIM2 inflammasome via certain pathways, thereby impacting MSU-induced gouty arthritis (79)

NAPQI can be immediately conjugated with glutathione (GSH) to form the non-toxic metabolites cysteine 3,4

Lowers total cholesterol levels, increases good cholesterol HDL, and lowers bad cholesterol LDL.(4) Improves blood sugar levels