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The STEP clinical trials showed average weight loss of approximately 15% of body weight over 68 weeks with lifestyle support

These can receive BUDs of 60 to 180 days depending on whether the preparation was aseptically processed or terminally sterilized, and whether sterility testing was performed

Key priorities include doseresponse optimization for acute versus chronic phases, inclusion of biomarkers such as glutathione reductase activity, neuroinflammatory cytokines, and imaging-based lesion metrics, and development of formulations that improve central nervous system bioavailability

However, it is relatively complex and time-consuming to perform, requiring a high level of expertise and experience (Prior et al

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Adhere to your doctor's monitoring and report sudden abdominal pain