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For most patients, the choice between the two comes down to a combination of clinical efficacy, personal preference, medical history, and the guidance of a qualified prescriber who can assess which is most appropriate for their individual circumstances

Safety Considerations and Who Should Seek Provider Consultation Tirzepatide is contraindicated in personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2

While sertraline is an effective treatment for many mental health conditions, it does come with potential side effects

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Cell B 42 , 3951 (2010)