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Strategies for Maintaining Long-Term GLP-1 Safety Several practical strategies can help maintain the long-term safety and tolerability of GLP-1 therapy while improving adherence

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In a substudy of 178 patients from the SUSTAIN 8 trial on semaglutide as a diabetes treatment, the average proportion of lean mass loss was nearly identical at 40%, despite lower doses and less total weight loss than in the STEP 1 trial