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It is a synthetic tetrapeptide composed of alanine, glutamic acid, aspartic acid, and glycine (Ala-Glu-Asp-Gly)

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Circulation 107:13591365 Yasumura EG, Stilhano RS, Samoto VY, Matsumoto PK, de Carvalho LP, Valero Lapchik VB, Han SW (2012) Treatment of mouse limb ischemia with an integrative hypoxia-responsive vector expressing the vascular endothelial growth factor gene

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keep a fast-acting carbohydrate (glucose tablets or juice) on hand and watch for hypoglycemia, especially during titration [6]