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Exogenous antioxidants: Vitamin C Vitamin E Carotenoids Polyphenols Zinc Selenium Endogenous antioxidants: Superoxide dismutase (SOD) Catalase (CAT) Glutathione peroxidase (GPx) Paraoxanase Glutathione S -transferase (GST) Glutathione Lipoic acid Bilirubin Melatonin Ubiquinol Uric acid Ferritin Transferrin Interventions Interventions below may vary depending on which genes in the oxidative stress panel are impacted

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Glucose-dependent insulinotropic polypeptide: a bifunctional glucose-dependent regulator of glucagon and insulin secretion in humans

Ribose 5-phosphate is an important building block for the biosynthesis of nucleotides, and erythrose 4-phosphate is used to synthesize aromatic amino acids

L.De SoyzaA.HaworthC

(2) Cross-nutrient common mechanistic gaps and future research directions Across all nutrient categories, three critical gaps in mechanistic understanding persist and must be addressed in future research: Quantification of microbiota-metabolite-depression thresholds: for example, the minimum amount of dietary fiber required to elevate fecal butyrate concentrations to levels that alleviate depressive symptoms remains unclear