Comprehensive toxicology studies found no lethal dose even at extremely high levels (20 mg/kg intramuscularly in rats, equivalent to approximately 1,400 mg for a 155 pound human)
If you are pregnant or nursing, taking medication, have a medical condition or planning surgery, consult a doctor before using this product
Hydroxycobalamin is equally as effective as cyanocobalamin, and they share the cobalamin molecular structure
Safety and side effects: A meta-analysis of multiple studies in COPD patients showed no significant adverse effects at doses ranging from 600 mg to 3g/day.[ref] Studies in healthy adult athletes go up to 20g/day (not recommending this, just including it for safety).[ref] Conversely, in Parkinsons patients, there was a high number of adverse events at 6g/day of NAC
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This is a more complicated question than it seems because obesity is so closely associated with increased cancer risk