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It is suggested that the activated BZ and NFX (and their metabolites), through direct binding to trypanothione (T[SH] 2 , N 1 ,N 8 -bisglutathionylspermidine) and GSH, make these antioxidants unavailable for the parasite's defense (Maya et al., 1997

Antioxidants are molecules with an extra electron to donate to free radicals

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However, abruptly stopping at a high dose can cause a rebound in appetite and blood sugar that feels dramatic

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