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its N-terminal 13-residue extension reduces IGF-binding-protein affinity and extends plasma half-life compared to native 70-amino-acid IGF-1

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Indeed, most studies do not incorporate sex as a discovery variable, and thus, in only a small proportion of studies, sex is used as a predictor variable or a between-subject variable to analyse for main and interaction effects rather than as a covariate [238, 239]

Additionally, real-time PCR was employed to assess the expression of lineage-specific markers: RUNX-2 and ALP for osteogenesis, and FABP4 and PPAR for adipogenesis

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