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2 New classes of medications, such as the dipeptidyl peptidase-4 (DPP-4) inhibitors, glucagon-like peptide-1 (GLP-1) receptor agonists, and sodium-glucose cotransporter- 2 (SGLT-2) inhibitors, specifically target some of the more recently identified defects described in the ominous octet to help manage uncontrolled hyperglycemia
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The GLP-1 medication, by contrast, is typically a long-term commitment in patients who have responded to it, with the literature generally supporting continued use to maintain the weight loss achieved