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Blood sampling was continued for another 30 min after completion of the exercise bout

FDA cited absence of a USP monograph, absence of an approved drug product, insufficient evidence of clinical need and safety, and nominator data inconsistencies between acetate and free base forms

It addresses both the dose and the bioavailability problem simultaneously

303 , E122E131 (2012)

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It is about the anxiety of potentially wasting expensive medication, the frustration of a mistake you cannot undo, and the worry about whether your treatment will be interrupted