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Six Biophysical screening methods miss a large proportion of crystallographically discovered fragment hits: a case study

Moreover, rats treated with 1% neohesperidin dihydrochalcone for 1 month showed reduced amygdala neuroinflammation via suppression of cAMP/PKA pathway activity, restoration of cortical 5-HT, DA, and NE levels, and reversal of anxiety- and depression-like behaviors (Jiang et al., 2023)

Ewert A, Leifheit-Nestler M, Hohenfellner K, Buscher A, Kemper MJ, Oh J, Billing H, Thumfart J, Stangl G, Baur AC, Foller M, Feger M, Weber LT, Acham-Roschitz B, Arbeiter K, Tonshoff B, Zivicnjak M, Haffner D (2020) Bone and mineral metabolism in children with nephropathic cystinosis compared with other CKD entities

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Gahl WA, Bashan N, Tietze F, Bernardini I, Schulman JD (1982) Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis