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In the experiment, untreated mice gained 9% of body weight, while obese mice treated with PTT lost nearly 19% of body weight

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Despite the initial belief that NEOs have low mammalian toxicity, there is growing evidence that NEOs can cause a wide range of toxic effects in animals and humans, including neurotoxicity, immunotoxicity, hepatotoxicity, nephrotoxicity, and reproductive cytotoxicity in vertebrates and invertebrates (Wang et al