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Mobile phases consisted in 0.1% formic acid in acetonitrile:water 95:5 (v/v, solvent A) and 0.1% formic acid in water (solvent B) both with 5 mM ammonium formate

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It regulates oxidative abilities of mitochondria and downregulated miR-107 was found to decrease mitochondrial volume, cristae and mitochondrial membrane potential