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Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R)

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Among participants on the 12mg dose, 91.7% achieved at least 10% body weight reduction by week 48

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GLP-1 receptor agonists should not replace evidence-based lipid management but may complement it in suitable patients

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Weight loss decelerates as you approach maintenance dose

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If you use the standard formulation, consider supplementing with B12 separately

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