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Many young boys with this syndrome show undescended testicles (Cryptorchidism), and while a hormone treatment called human chorionic gonadotropin may be effective, most of them need a surgical procedure called orchiopexy. Hormone replacement therapy may be indicated for delayed puberty, and consultation with an endocrinologist is recommended at puberty

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Since the body of a well-trained athlete is already highly sensitive to insulin, any unnatural increase in insulin could throw them off balance, and result in a dangerously low blood sugar level, Quebbemann says