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107 Another placebo-controlled crossover trial by the same research group found 3 grams of tryptophan nightly for seven nights improved sleep quality scores in 57 carriers of the genetic variant of interest and high susceptibility to stress

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10.1016/j.molmet.2020.100990 [DOI] [PMC free article] [PubMed] [Google Scholar] Parker, H

Bacterial contamination accelerates peptide degradation and could theoretically cause infection, though the sublingual vehicle itself often contains antimicrobial properties

the most common reason was adversereactions (n=48, 5.3%)