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Tesamorelin is an FDA-approved treatment for reducing abdominal fat in HIV-infected patients with lipodystrophy, while ipamorelin has yet to complete human clinical trials and is typically administered in conjunction with a GHRH like tesamorelin or CJC-1295

Of note, integrating TCM into standard care was constrained by methodological limitations (e.g., small sample sizes, non-RCT designs), mechanistic ambiguity, and quality control issues, necessitating large-scale randomized trials, ingredient standardization, and safety evaluations to facilitate evidence-based implementation

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Eli Lillys diabetes drug, tirzepatide, also known as Mounjaro, is expected to be approved by the FDA for weight loss in 2023

doi:10.3945/an.115.011221 Elango, R., Ball, R

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