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Higher concentrations (3%+) are best reserved for experienced users or targeted use, as they raise the risk of irritation and staining without clearly proportional benefits

Tendons are notoriously slow to heal, because they barely have a blood supply

Treatment starts at 0.25 mg weekly for four weeks to improve tolerability, then typically increases to 0.5 mg, with further escalation to 1 mg or 2 mg if needed

By increasing tight junction proteins, decreasing intestinal permeability, and lowering endotoxemia a known cause of vascular inflammation and atherogenesis probiotics also improve the integrity of the gut barrier

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