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In published clinical trials, once weekly cagrilintide has been reported to produce dose dependent body weight reductions in participants with overweight or obesity, and it has also been studied in combination programmes with semaglutide, where trials reported greater weight loss than either component alone

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It has been extensively studied in animal models for its regenerative effects across multiple tissue types, including tendon, ligament, vascular endothelium, muscle, and intestinal mucosa

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