In conclusion, for individuals with type 2 diabetes, tirzepatide treatment, compared with semaglutide, significantly improved achievement of guideline-recommended standard and intensive therapeutic goals, potentially enhancing long-term prognosis
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I-05 Assessment of risk and benefit in clinical trials: Challenges in rare diseases Bruce Zuraw University of California, San Diego, CA, USA Allergy, Asthma & Clinical Immunology 2025, 21(Suppl 2) :I-05 The ethical principles underlying clinical research developed over the past 80 years are well-established and universally accepted