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2023ZD0503400 and 2023ZD0503403) and the National Key Research and Development Program of China (Grant Nos

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Future studies are needed to clarify the detailed mechanisms by which GIP influences appetite, weight regulation, and metabolic processes in both central and peripheral contexts

This strategy not only effectively eradicates orthotopic and distal tumors but also enhances the bodys antitumor immune response, offering a promising new approach for CRC therapy

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As a sensitivity analysis, we performed landmark analyses at these timepoints, including only patients who were event-free and remained on treatment to examine the associations with subsequent outcomes