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Drucker DJ, Nauck MA (2006) The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes

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We, therefore, used alternative approaches and have determined the structure of a high molecular weight TrxR subfamily member using cryo-EM, demonstrating the feasibility of this methodology to study this protein subfamily of importance in several human diseases (PDB ID 8A1R, EMD-15084) (Fig

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These findings provide mechanistic insights into how tryptophan metabolism mediated by gut microbiota influences CKD progression and identify a potential therapeutic target for intervention

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