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Combinations of Treatment Methods As GLP-1 RA and amylin analog-induced weight loss arise from both distinct and overlapping mechanisms, the combination of GLP-1 RA and amylin RA has been shown to produce a synergistic effect [118]
used a tetracycline-response element to control in vivo expression of a short-hairpin RNA against Trp53 [138], the mouse analog of TP53
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10.1097/SLA.0b013e31819a4789 75
Keatings VM, Barnes PJ
Risk factors that should prompt consideration of B12 deficiency include advancing age (reduced stomach acid production), strict vegan or vegetarian diets, pernicious anaemia, gastrointestinal surgery (particularly gastric bypass or ileal resection), long-term use of certain medications (metformin, proton pump inhibitors, H2-receptor antagonists), nitrous oxide exposure (including recreational use), and conditions affecting the gut such as Crohn's disease or coeliac disease
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