Hydrogen peroxide is mainly neutralized by the enzyme catalase, which turns hydrogen peroxide into water and oxygen, and the tripeptide glutathione (GSH), which converts hydrogen peroxide into water through a reducing reaction catalyzed by the enzyme glutathione peroxidase (GPX)
In neurodegenerative diseases like Alzheimers and Parkinsons, antioxidants may help protect neurons from oxidative damage and slow disease progression [199]
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Importantly, among children with the AG + AA genotype for rs6970396 Se metabolizing indolethylamine N-methyltransferase gene (INMT), an inverted U-shaped association between Se and neuropsychological development was identified, albeit a descending curve was indicated for the GG genotype [28]