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How many times might it need replacement

Several large clinical studies, the majority of which are cardiovascular outcome trials, indicate that GLP-1 RA therapy is safe and tolerable for people living with T2DM and compromised renal function, and also suggest that GLP-1 RAs may have renoprotective properties

Ozempic takes about 5 weeks after your last dose to leave your system completely

When to seek medical advice You should seek medical advice if you experience: Severe or persistent fatigue that lasts more than a few weeks despite self-care

Importantly, given the sexually dimorphic nature of MASLD [53] that could potentially affect therapy response [5456], there have been no male-to-female comparative studies conducted to determine if one sex responds better to tirzepatide