With respect to body weight, a higher baseline body-mass-index is a predictor of absolute weight reduction, albeit with substantial body weight loss even in those with a BMI 50 years with either chronic kidney disease and an eGFR of less than 60 ml/min per 1.73 m 2 or history of congestive heart failure (NY Heart Association Class II or III)
It should be noted that this study focussed on participants nave to treatment with injectable glucose-lowering therapy, with no individuals reporting prior GLP-1RA experience at baseline
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doi: 10.1186/1471-2318-8-36
Effect of chronic oxidative stress on neuroinflammatory response mediated by CD4+T cells in neurodegenerative diseases