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Glutathione plays a variety of roles in the body, including: regenerating other antioxidants (e.g., vitamin C, vitamin E) neutralizing free radicals detoxification of certain drugs regulating the immune system managing inflammation supporting various bodily systems (e.g., nervous system, pulmonary system) delaying cell aging Glutathione depletion is also linked to numerous health issues, including increased susceptibility to infectious diseases and illnesses, oxidative stress, and certain chronic diseases, such as type 2 diabetes, certain types of cancer, kidney disease, neurodegenerative disease, liver disease, and cardiovascular disease ( 1 , 2 )

2018;57:115764 European Agency for Safety and Health at Work

Moreover, drugs targeting mutant isocitrate dehydrogenase in acute myeloid leukemia (AML) have marked a milestone in precision cancer metabolism therapy, demonstrating the potential effectiveness of metabolic treatment ( Due to its extensive clinical application experience and wide accessibility, traditional Chinese Medicine (TCM) plays a crucial role in cancer treatment in China ( Above all, targeting cancer metabolic abnormalities has been recognized as a promising strategy to remodel the tumor microenvironment and enhance antitumor immune responses

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