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*Correspondence: Ana Karina Zambrano, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Some patients report improved leg pain, softer nodules, reduced tenderness in lipedema areas, and decreased knee pain

The baseline HbA1c in the tirzepatide arms was 8.23%8.36% and 8.37% in the placebo group

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We recommend pairing injections with a balanced diet and regular physical activity to maximize and maintain your results after treatments have ended