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Handling and Storage Recommendations To preserve sample integrity and support safe laboratory practices, the following guidelines should be followed: Store at 20 C or below (non-frost-free preferred)

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This starts the 28-day stability clock

This suggests that both biological and environmental factors play a role in determining vitamin B12 status, highlighting the need for targeted nutritional interventions in vulnerable populations

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Since vitamin B12 is primarily found in animal products, those who avoid meat, dairy, or eggs may develop low B12 levels over time