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GLP1 receptor agonist use was not associated with increased risk of thyroid cancer (hazard ratio 0.93)

Image Credit: zimmytws / Shutterstock In a recent article published in the journal JMIR Infodemiology , researchers analyzed public Facebook posts to examine public discussion of adverse effects associated with glucagon-like peptide-1 receptor agonists (GLP-1 RAs)

Sirtuin 1-mediated deacetylation of XPA DNA repair protein enhances its interaction with ATR protein and promotes cAMP-induced DNA repair of UV damage

In a 2024 literature review published in the Journal of the American Pharmacists Association that assessed six clinical trials , researchers found that tirzepatide had a greater impact on absorption of oral hormonal contraceptives compared with other GLP-1s

Even with weekly injections for a full year, the cumulative weekly B6 dose from the compound alone ranges from 5 to 10 mg, far below the levels associated with neuropathy

Chen et al., 2000)