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Fluoride ions(F - ) facilitate the deposition of calcium ions (Ca 2+ ) and phosphorus ions (PO 4 ) within the tooth structure, forming more acid-resistant fluorapatite (Ca 5 (PO 4 ) 3 F), while also buffering the acidic environment created by bacteria

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However, rapid conversion of this reduced GSH into oxidized glutathione or glutathione disulfide (GSSG) can occur through different biochemical reactions within different compartments, and especially during adverse or stress conditions

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