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Methylation and methyl donor status NNMT consumes methyl donors as part of its enzymatic function

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In research studies it may be appropriate to use log (HOMA-IR) instead of HOMA

While the biochemical mechanisms underlying the neurological effects of vitamin B 12 deficiency are not understood, the vitamin deficiency is known to damage the myelin sheath covering cranial, spinal, and peripheral nerves (42, 43)

Hu et al., 2014