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Dalam basis krim dan losion, konsentrasi antara 0.05 dan 0.2 persen bekerja efektif ketika dilarutkan terlebih dahulu dalam fase air sebelum emulsifikasi

They could be diluted, making them less effective, or blended with other ingredients, such as B vitamins, in formulations that haven't undergone rigorous testing

Front Physiol 10:1601

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Even if patients have appropriate glycemic control, their medication regimen may not be optimal based on co-morbidities