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[DOI] [PubMed] [Google Scholar] Gillessen, A

doi:10.1007/s11136-016-1335-1 Mari A, Hosadurg D, Martin L, Zarate-Lopez N, Passananti V, Emmanuel A

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Discovery of a novel NAMPT inhibitor that selectively targets NAPRT-deficient EMT-subtype cancer cells and alleviates chemotherapy-induced peripheral neuropathy

[1] Orforglipron: A Milestone in Oral GLP-1 RA Development Eli Lilly also presented positive topline Phase 3 results from ACHIEVE-1, evaluating the safety and efficacy of orforglipron compared to placebo in adults with type 2 diabetes and inadequate glycemic control with diet and exercise alone

Research confirms that concerns arise from notable reductions in lean mass, especially as they relate to metabolic adaptation and physical function