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Upon activation by dsDNA, cGAS catalyzes the synthesis of cGAMP from ATP and GTP

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Clinical endocrinology 81 , 458466 (2014)

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Gafni-Kane A, Botros SM, Du H et al: Measuring the success of combined intravesical dimethyl sulfoxide and triamcinolone for treatment of bladder pain syndrome/interstitial cystitis

The severity of the curvature and the presence of penile plaque can affect urinary function, potentially leading to urinary tract infections, urinary retention, and incomplete emptying of the bladder