However, you should know there are some more serious, but rare, complications that can occur: Pancreatitis (painful inflammation of the pancreas, the organ that produces insulin and other digestion-related substances) Medullary Thyroid Cancer (a rare type of thyroid cancer) Acute Kidney Injury (sudden damage to the kidneys) Worsening of Diabetic Retinopathy (eye problems caused by diabetes)1 Severe Vomiting and Diarrhea (this can be very dangerous if its not addressed) Jaundice (yellow skin color caused by a buildup of waste products in the blood)5 If you experience any severe or persistent side effects, it is very important to contact your doctor right away

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Peer review Peer review information Nature Reviews Rheumatology thanks Helena Marzo-Ortega, who co-reviewed with Jacob Williams
Devices that provide real-time feedback improve adherence and help clinicians fine-tune therapy
Hydration and Lifestyle Stay well hydrated: Dehydration worsens nausea and fatigue
Cell 185 , 37393752 (2022)