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This work was supported by the US National Institutes of Health (R01AT008618, R01HL122593 and F32DK101154), the Young Investigator Grant for Probiotics Research, the George Williams Hooper Research Foundation and the University of California San Francisco (UCSF) Department of Microbiology & Immunology

Furthermore, it discusses the mechanisms, types, and applications of nanoparticle systems in vaccine innovation, as well as the opportunities and challenges that define their path toward more effective, stable, and globally accessible immunization strategies