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These typically subside as the body adapts to treatment

However, there is also evidence pointing toward a hepatic origin of circulating DPP-4, and it has been suggested that the inclusion of some patients with unidentified liver disease may have contributed to the conflicting data regarding the association of plasma DPP-4 activity and T2DM

But if the next dose is less than two days away, they should not take the skipped dose and resume their regular schedule