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Further studies are needed to confirm the actual benefit of this molecule on metabolic liver diseases and define the best route of administration and the most appropriate dosage, allowing its use in clinical practice

No evidence it causes cancer but could feed existing cancer

Widenmaier SB, Kim SJ, Yang GK, De Los Reyes T, Nian C, Asadi A, et al

What this study adds: We also confirm cognitive deficits in IIH patients with raised ICP notably in executive function

222 SIRT3 also plays a regulatory role in proline metabolism via deacetylation of PYCR1