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From a translational perspective, phoenixin exemplifies a class of peptides whose underexplored status reflects conservatism in trial design rather than a lack of biological plausibility

This progressive destruction of thyroid tissue leads to reduced production of thyroid hormonesprimarily thyroxine (T4) and triiodothyronine (T3)which are essential for regulating metabolism, energy production, and numerous bodily functions

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They are not a substitute for a varied and balanced diet and a healthy lifestyle