glp 1 agonist euglycemic dka GLP-1 Receptor Agonists as Treatments for Type 2 Diabetes Proposed role of sodium-glucose cotransporter

Future randomised controlled trials should specifically evaluate the effectiveness of novel AOMs for long-term weight management in older adults with obesity, carefully considering the impact on body composition and functional ability, as well as health economics

Chen XW, He ZX, Zhou ZW, Yang T, Zhang X, Yang YX, et al

535 p53 can accelerate ferroptosis and the development of atherosclerosis by binding to SLC7A11, preventing the synthesis of GSH, and increasing the hydrolysis of GSH and the production of ROS by activating glutaminase 2

SURPASS-1 shows that tirzepatide alone, at all doses, was superior to placebo and revealed a dose-dependent reduction of HbA1c by up to 2.07% (p 10% weight loss can be disease modifying and may even lead to disease remission [38]

This study offers important considerations for healthcare professionals (HCPs) regarding how T1D diagnosis influences Tzield treatment in routine practice

Consider a formulation switch as a personal experiment