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Arterioscler Thromb Vasc Biol (2015) 35(3):48591

According to Eli Lilly, the most common side effects of Zepbound (tirzepatide) are: Constipation Decreased appetite Diarrhea Fatigue Hair loss Heartburn and belching Indigestion Injection site reactions Nausea Stomach pain Vomiting In studies, most reactions like nausea, vomiting, and diarrhea occurred when people increased their dose but the effects generally decreased over time

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In the absence of large-scale, controlled studies, any inference of a causal link remains speculative

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In July 2021, AstraZeneca, a multinational biotechnology company, announced that its product BYDUREON BCise (exenatide extended-release), a once-weekly injectable suspension, had been approved in the U.S