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In addition, it has been shown that glucagon enhances hepatic lipid metabolism and reduces food intake in rodents and humans

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Sorathia SJ, Rivas JM

Triplehormone-receptor agonist retatrutide for obesity A phase 2 trial

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Apart from being generated by the gut microbiome, acetate can be consumed as such in the forms of vinegar (~1 g/day) or fermented foods such as pickles, sauerkraut, kimchi, yogurt, cheese, and kombucha, or as a food additive (~2 g/day)