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Cyanocobalamin: Key Differences Methylcobalamin differs from cyanocobalamin by skipping the need for liver conversion and being readily available for cell use away.This quick absorption leads to longer-lasting benefits,namely in the treatment of neurological conditions

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What this means for dosing calculations: the clinical trial protocols use fixed escalation schedules with specific dose targets (typically 8mg or 12mg maintenance)

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10.1038/ajg.2011.315 Am J Gastroenterol