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For example, a 10 mg vial with 1 mL of water gives 10 mg/mL

Moreover, patients with T2DM have impaired incretin action, which highlights GLP-1 as a useful pharmacotherapy for restoring glucose control (reviewed in Madsbad, 2014)

Advertisement While semaglutide works to mimic GLP-1 hormones, tirzepatide (like Mounjaro and Zepbound) is considered a dual agonist

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In its first year on the market in T2DM (2022), Mounjaro brought in $483 million in global sales

Similar to previous reports, many EECs were multihormonal 81,87 , and many subtypes within EECs may not be distinct lineages but rather are separate stages in EEC maturation 86