Glutathione one of the most important and powerful antioxidants most important and powerful antioxidants Glutathione (GSH) is an endogenous peptide compound found in virtually all human cells and is a component of important enzymes
72,73 The increase in intracellular cAMP after GLP-1R activation then activates a guanine nucleotide exchange factor called Epac (Exchange Protein directly Activated by cAMP), which induces PI3K activation followed by Akt phosphorylation
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Cell Rep 19:12021213 Lu C-C, Huang W-S, Lee K-F, Lee K-C, Hsieh M-C, Huang C-Y et al (2016) Inhibitory effect of Erinacines A on the growth of DLD-1 colorectal cancer cells is induced by generation of reactive oxygen species and activation of p70S6K and p21