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Bone Healing: Preclinical research has investigated: Acceleration of fracture healing in rodent models Improved callus formation and bone density Enhanced integration of bone grafts Potential effects on osteoblast and osteoclast activity For dogs recovering from fracture repair surgeries or orthopedic procedures, these mechanisms could theoretically support healing, though clinical evidence specific to canines is limited

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Niacinamide and Licorice Extract work together to de-pigment and even out skin tone, while Tremella Fuciformis, Ginseng Root Extract, and Jojoba Seed Oil nourish and protect against daily environmental damage and pollution

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Several of the DEGs were TF genes, including Klf4 and Klf5 , (Extended Data Fig