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In conclusion, GGT and the ChaC family of GSH degrading enzymes, both intracellularly and extracellularly, are key for maintaining GSH homeostasis and serve key roles in normal cellular processes and tumor-related stress conditions

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BPC-157 upregulates VEGFR2 expression in vascular endothelial cells at both mRNA and protein levels without increasing VEGF-A production, suggesting the peptide sensitizes endothelial cells to existing VEGF rather than simply increasing ligand availability

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[DOI] [PubMed] 9.Gnalan E, Yaba A, Ylmaz B